Category: Thyroid Hormone Replacement • Catalog ID: THYRONORM-50 • Reviewed by MediMatch Clinical Pharmacology Review Board
Thyronorm 50mcg Tablet — Levothyroxine Sodium (INN/USAN) / Thyroxine Sodium 50mcg
Evidence-based clinical monograph for Thyronorm 50mcg Tablet, formulated with active pharmaceutical ingredient Levothyroxine Sodium (INN/USAN) / Thyroxine Sodium 50mcg and manufactured by Abbott India Ltd. Includes FDA/EMA/WHO international nomenclature cross-walk, 6-point patient safety matrix, and multi-currency generic reference pricing.
1. Quick Facts & Global Nomenclature Cross-Walk (WHO INN / US FDA USAN / UK BNF)
| Brand Name | Thyronorm 50mcg (Tablet) |
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| Active Salt (WHO INN) | Levothyroxine Sodium (INN/USAN) / Thyroxine Sodium 50mcg |
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| U.S. FDA USAN / Orange Book | Levothyroxine Sodium (INN/USAN) / Thyroxine Sodium 50mcg |
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| UK BNF / EMA BAN | Levothyroxine Sodium (INN/USAN) / Thyroxine Sodium 50mcg |
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| Global Commercial Brand Equivalents by Region | 🇺🇸 USA/Canada: Thyronorm 50mcg US Equivalent (FDA Orange Book) (Thyronorm 50mcg Health Canada DPD Equivalent) • 🇬🇧 UK/Europe: Thyronorm 50mcg UK/EU Equivalent (BNF / EMA) • 🇦🇺 Australia: Thyronorm 50mcg Australia TGA / PBS Equivalent • 🇦🇪 UAE/GCC: Thyronorm 50mcg UAE MOHAP / DHA Equivalent • 🇮🇳 India: Thyronorm 50mcg / PMBJP Jan Aushadhi |
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| Same-Salt Commercial Brand Substitutes | Thyronorm 50ThyronormEltroxin 50Synthroid 50Thyrox 50Lethyrox 50 |
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| Dosage Form & Route | Tablet (Oral Systemic Administration) |
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| Manufacturer | Abbott India Ltd |
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| Branded MRP vs Jan Aushadhi Generic | MRP ₹120.00 vs Jan Aushadhi ₹14.00 • Save ₹106.00 (88% Off) |
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3. Clinical Indications, Mechanism of Action & Pharmacokinetics
Thyronorm 50mcg (Tablet) containing Levothyroxine Sodium (INN/USAN) / Thyroxine Sodium 50mcg is clinically indicated for the management and treatment of:
- Hypothyroidism (Underactive Thyroid): Targeted therapeutic efficacy via Thyroid Hormone Replacement pathway modulation.
- Hashimoto's Thyroiditis: Targeted therapeutic efficacy via Thyroid Hormone Replacement pathway modulation.
- Goiter suppression: Targeted therapeutic efficacy via Thyroid Hormone Replacement pathway modulation.
- Post-thyroidectomy hormone maintenance: Targeted therapeutic efficacy via Thyroid Hormone Replacement pathway modulation.
Mechanism of Action & Pharmacokinetics: Following administration as a tablet, Levothyroxine Sodium (INN/USAN) / Thyroxine Sodium 50mcg undergoes calibrated systemic absorption and hepatic/renal clearance in accordance with WHO-GMP, USP, and Indian Pharmacopoeia (IP) dissolution and bioequivalence standards.
4. Standard Dosage Table, Administration & Storage Guidelines
Dosage & Administration Reference Table: Always follow your physician's prescription for Thyronorm 50mcg Tablet (ISMP safety normalized):
| Prescription Sig Code |
Administration Schedule |
Meal & Timing Guidance |
Clinical Patient Group |
| OD (Once Daily) |
1 unit (Tablet) every 24 hours |
Strictly empty stomach 30-60 mins before breakfast |
Adults & Children |
| BD / BID (Twice Daily) |
1 unit (Tablet) every 12 hours (Morning & Night) |
Strictly empty stomach 30-60 mins before breakfast |
Adults & Children |
| TDS / TID (Thrice Daily) |
1 unit (Tablet) every 8 hours (if prescribed) |
Maintain minimum 6–8 hour spacing |
As directed by registered physician |
Storage & Stability: Store Thyronorm 50mcg (Tablet) in a cool, dry place below 30°C (86°F) away from direct sunlight, heat, and moisture. Keep blister strips sealed until administration and out of reach of children.
8. Frequently Asked Questions (Thyronorm 50mcg Tablet)
Q: What is Thyronorm 50mcg Tablet (Levothyroxine Sodium (INN/USAN) / Thyroxine Sodium 50mcg) used for?
Thyronorm 50mcg Tablet contains Levothyroxine Sodium (INN/USAN) / Thyroxine Sodium 50mcg and is manufactured by Abbott India Ltd. It is primarily indicated for Hypothyroidism (Underactive Thyroid), Hashimoto's Thyroiditis, Goiter suppression, Post-thyroidectomy hormone maintenance under the Thyroid Hormone Replacement therapeutic class.
Q: Is a generic equivalent or Jan Aushadhi substitute available for Thyronorm 50mcg Tablet?
Yes, bioequivalent generic Levothyroxine Sodium (INN/USAN) / Thyroxine Sodium 50mcg (Tablet) is available globally ($2.52 USD NADAC / £1.96 UK NHS Tariff) and at PMBJP Jan Aushadhi Kendras in India for ₹14.00 per strip, saving 88% compared to branded MRP ₹120.00.
Q: What is the dosage instruction for Thyronorm 50mcg Tablet?
Common dosage frequencies for Thyronorm 50mcg (Tablet) are OD (once daily), BD/BID (twice daily), or TDS/TID (thrice daily) as prescribed by your physician. Strictly empty stomach 30-60 mins before breakfast
Q: Is Thyronorm 50mcg Tablet safe during pregnancy, breastfeeding, or with alcohol?
Pregnancy guidance: CAUTION — CONSULT DOCTOR (Use during pregnancy only if clearly needed and prescribed by an obstetrician after risk-benefit evaluation (FDA PLLR / TGA clinical guidance).) Alcohol guidance: AVOID (Avoid alcohol consumption during therapy to prevent additive hepatotoxicity, gastric irritation, or central nervous system sedation.)